Genome Medicine

About this programme

This course aims to provide you with an understanding of the use of genome and epigenome information in medicine. It will give an advanced introduction to epigenetics and its role in health and disease. You will work in a project to design a theoretical experiment setup to find the genetic causes of given diseases. Please note that Students not located in Sweden may have problems attending a course at KTH. You could meet obstacles if you're required to pay fees or if you do not have a Swedish Mobile BankID. Please note: all information from the Course syllabus is available on this page in an accessible format. The course will be given online and aims to provide students an understanding of the use of genome and epigenome information in medicine. The course will give an advanced introduction to epigenetics and its role in health and disease, cancer, gene therapy and genome editing. The following topics will be included in the course: We will discuss the organisation and the type of mutations in the human genome. We will then look at its interplay with epigenetic mechanisms as well as the role of 3D structure of the genome in gene regulation. We will then focus on the genetic architecture of monogenic and complex diseases and strategies to find causative or contributing genetic factors involved in disease onset. The impact of genome variation will be exemplified with cancer, rare and complex diseases. Strategies for diagnosis and treatment of the diseases are covered, such as gene and stem cell therapy. Diseases related to polymerization and structural changes of proteins