Advanced Neurochemistry with Molecular Neurobiology

About this programme

The starry night in co-culture. In blue in this image we can see skeletal muscle fibers that should represent clouds in a night sky, and in yellow the moon that is a sphere of motor neurons, we called it Co-culture cause we grow together muscle and motor-neurons derived from hIPSC. Photo: Irene Mei and Lara Leal Hernandez Emphasis will be placed on the development of the nervous system, the interplay between glia cells and neurons, the role of cytokines and neurotrophic factors, and how these molecules regulate gene expression and thus different cellular functions in cells of the nervous system. The course will cover glial and neuronal functions/dysfunction in response to physical trauma, as well as in neuropsychiatric, neuroinflammatory and neurodegenerative diseases. The problems and possibilities with neuronal regeneration will also be discussed. An additional focus of the course is to learn about different methods and models that can be used to study the nervous system in health and disease. Laboratory exercises and the project work will give practical experience of some models and methods , which includes training in eukaryotic cell culturing, including human induced pluripotent stem cells. Students will also learn how to present and analyze research data in a scientific manner. Previous knowledge equivalent to the course Neurochemistry with molecular neurobiology (KN7001) is required in order to enroll in this course. Theory part (8 ECTS): The theory part consist of lectures, which includes small theoretical exercises to facilitate learning of the lecture material.