Bioanalytical chemistry

About this programme

An overview of basic concepts and approaches in genomics, proteomics, metabolomics is given as well as a survey of the field of drug development. Students will study a range of analytical techniques used for sample pre-treatment, detection, identification, and quantification of biomolecules, including immunoassay, biomolecular mass spectrometry, biosensors and clinical diagnostics and imaging techniques. The interplay of experimental and computational approaches is also explored. The course features lectures, workshops, laboratory project work, oral and written presentation of scientific work within the following subjects: Bioanalytes Overview of the range of analytes relevant in bioanalytical chemistry, including nucleic acids, proteins, lipids, metabolites, handling of biological samples, sample preparation and storage methods. Immunoassays Concepts and cutting edge applications of molecular recognition assays, including clinical diagnostics and point-of-care analysis. Biosensors Concepts and applications of optical and electrochemical biosensors, including concepts around wearable sensors. Biomolecular mass spectrometry Concepts and applications for native mass spectrometry, analyses of biomolecular complexes, and analysis of complex biological matrices. Imaging techniques for example, optical spectroscopy, mass spectrometry or X-ray-based techniques Drug development The process and chain of drug development, from inception to testing and trials Additional methods of interest could include Blotting techniques, nucleic acid amplification techniques, nanopores and